80 research outputs found

    Extraction of Daily Life Log Measured by Smart Phone Sensors Using Neural Computing

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    AbstractThis paper deals with the information extraction of daily life log measured by smart phone sensors. Two types of neural computing are applied for estimating the human activities based on the time series of the measured data. Acceleration, angular velocity, and movement distance are measured by the smart phone sensors and stored as the entries of the daily life log together with the activity information and timestamp. First, growing neural gas performs clustering on the data. Then, spiking neural network is applied to estimate the activity. Experiments are performed for verifying the effectiveness of the proposed method

    Induction of antigen-specific tolerance through hematopoietic stem cell-mediated gene therapy: the future for therapy of autoimmune disease?

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    Based on the principle that immune ablation followed by HSC-mediated recovery purges disease-causing leukocytes to interrupt autoimmune disease progression, hematopoietic stem cell transplantation (HSCT) has been increasingly used as a treatment for severe autoimmune diseases. Despite clinically-relevant outcomes, HSCT is associated with serious iatrogenic risks and is suitable only for the most serious and intractable diseases. A further limitation of autologous HSCT is that relapse rates can be high, suggesting disease-causing leukocytes are incompletely purged or the environmental and genetic determinants that drive disease remain active. Incorporation of antigen-specific tolerance approaches that synergise with autologous HSCT could reduce or prevent relapse. Further, by reducing the requirement for highly toxic immune-ablation and instead relying on antigen-specific tolerance, the clinical utility of HSCT could be significantly diversified. Substantial progress has been made exploring HSCT-mediated induction of antigen-specific tolerance in animal models but studies have focussed on primarily on prevention of autoimmune diseases. However, as diagnosis of autoimmune disease is often not made until autoimmune disease is well developed and populations of autoantigen-specific pathogenic effector and memory T cells have become well established, immunotherapies must be developed to address effector and memory T-cell responses which have traditionally been considered the key impediment to immunotherapy. Here, focusing on T-cell mediated autoimmune diseases we review progress made in antigen-specific immunotherapy using HSCT-mediated approaches, induction of tolerance in effector and memory T cells and the challenges for progression and clinical application of antigen-specific ‘tolerogenic’ HSCT therapy

    Boolean functions for homomorphic-friendly stream ciphers

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    The proliferation of small embedded devices having growing but still limited computing and data storage facilities, and the related development of cloud services with extensive storage and computing means, raise nowadays new privacy issues because of the outsourcing of data processing. This has led to a need for symmetric cryptosystems suited for hybrid symmetric-FHE encryption protocols, ensuring the practicability of the FHE solution. Recent ciphers meant for such use have been introduced, such as LowMC, Kreyvium, FLIP, and Rasta. The introduction of stream ciphers devoted to symmetric-FHE frameworks such as FLIP and its recent modification has in its turn posed new problems on the Boolean functions to be used in them as filter functions. We recall the state of the art in this matter and present further studies (without proof)

    A review of advanced catalyst development for Fischer-Tropsch synthesis of hydrocarbons from biomass derived syn-gas

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    Fischer-Tropsch synthesis (FTS) is a process which converts syn-gas (H2 and CO) to synthetic liquid fuels and valuable chemicals. Thermal gasification of biomass represents a convenient route to produce syn-gas from intractable materials particularly those derived from waste that are not cost effective to process for use in biocatalytic or other milder catalytic processes. The development of novel catalysts with high activity and selectivity is desirable as it leads to improved quality and value of FTS products. This review paper summarises recent developments in FT-catalyst design with regards to optimising catalyst activity and selectivity towards synthetic fuels

    Defining Contemplative Science : The Metacognitive Self-Regulatory Capacity of the Mind, Context of Meditation Practice and Modes of Existential Awareness

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    The term 'contemplative' is now frequently used in the fast growing field of meditation research. Yet, there is no consensus regarding the definition of contemplative science. Meditation studies commonly imply that contemplative practices such as mindfulness or compassion are the subject of contemplative science. Such approach, arguably, contributes to terminological confusions in the field, is not conducive to the development of an overarching theory in contemplative science, and overshadows its unique methodological features. This paper outlines an alternative approach to defining contemplative science which aims to focus the research on the core capacities, processes and states of the mind modified by contemplative practices. It is proposed that contemplative science is an interdisciplinary study of the metacognitive self-regulatory capacity (MSRC) of the mind and associated modes of existential awareness (MEA) modulated by motivational/intentional and contextual factors of contemplative practices. The MSRC is a natural propensity of the mind which enables introspective awareness of mental processes and behavior, and is a necessary pre-requisite for effective self-regulation supporting well-being. Depending on the motivational/intentional and contextual factors of meditation practice, changes in the metacognitive self-regulatory processes enable shifts in MEA which determine our sense of self and reality. It is hypothesized that changes in conceptual processing are essential mediators between the MSRC, motivational/intentional factors, context of meditation practice, and the modulations in MEA. Meditation training fosters and fine-tunes the MSRC of the mind and supports development of motivational/intentional factors with the ultimate aim of facilitating increasingly advanced MEA. Implications of the proposed framework for definitions of mindfulness and for future systematic research across contemplative traditions and practices are discussed. It is suggested that the proposed definition of contemplative science may reduce terminological challenges in the field and make it more inclusive of varied contemplative practices. Importantly, this approach may encourage development of a more comprehensive contemplative science theory recognizing the essential importance of first- and second-person methods to its inquiry, thus uniquely contributing to our understanding of the mind

    A novel multimodal communication framework using robot partner for aging population

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    In developed country such as Japan, aging has become a serious issue, as there is a disproportionate increasing of elderly population who are no longer able to look after themselves. In order to tackle this issue, we introduce human-friendly robot partner to support the elderly people in their daily life. However, to realize this, it is essential for the robot partner to be able to have a natural communication with the human. This paper proposes a new communication framework between the human and robot partner based on relevance theory as the basis knowledge. The relevance theory is implemented to build mutual cognitive environment between the human and the robot partner, namely as the informationally structured space (ISS). Inside the ISS, robot partner employs both verbal as well as non-verbal communication to understand human. For the verbal communication, Rasmussen's behavior model is implemented as the basis for the conversational system. While for the non-verbal communication, environmental and human state data along with gesture recognition are utilized. These data are used as the perceptual input to compute the robot partner's emotion. Experimental results have shown the effectiveness of our proposed communication framework in establishing natural communication between the human and the robot partner

    A Study of Population Size and Activity Patterns and Their Relationship to the Prey Species of the Eurasian Lynx Using a Camera Trapping Approach

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    Revealing the behavioral relationships between predators and their prey is fundamental in understanding the community structure and ecosystem functions of such animals. This study aimed at detecting the population size and activity patterns of Eurasian lynx (Lynx lynx) (along with its prey) by camera trapping monitoring from 2014 to 2017 at the Saihanwula nature reserve in central Inner Mongolia. The total effective trapping days were 29,892 and 20 lynx were identified from 343 trapping photos based on the inner side patterns of their forelimbs. The daily activity rhythms of the lynx overlapped with those of different prey in different seasons. The yearly activity pattern of the lynx was influenced by its main prey’s biology. In conclusion, this study reveals that the activity patterns of the top predator matched those of its prey in different time periods. Habitat management strategies promoting the restoration of prey communities would benefit the lynx in maintaining a stable community structure
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